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Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience

Breast cancer is a multifaceted disease that currently represents a leading cause of death in women worldwide. Over the past two decades (1998–2020), the National Health Laboratory Service’s Human Genetics Laboratory in central South Africa screened more than 2,974 breast and/or ovarian cancer patie...

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Detalles Bibliográficos
Autores principales: Van der Merwe, Nerina C., Combrink, Herkulaas MvE, Ntaita, Kholiwe S., Oosthuizen, Jaco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024354/
https://www.ncbi.nlm.nih.gov/pubmed/35464868
http://dx.doi.org/10.3389/fgene.2022.834265