Pharmacokinetics, Tissue Distribution, Metabolism and Excretion of a Novel COX-2 Inhibitor, Vitacoxib, in Rats

The objectives of this study were to elucidate absorption, tissue distribution, excretion, and metabolism of vitacoxib, a novel selective cyclooxygenase-2 inhibitor, in Wistar rats. Vitacoxib was detected in most tissues within 15 min, suggesting that it was well distributed. Moreover, it could cros...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jianzhong, Kong, Jingyuan, Yang, Yuxin, Liu, Yu, Qiu, Jicheng, Gong, Xiaohui, Zhang, Lu, Li, Jing, Sun, Feifei, Cao, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024361/
https://www.ncbi.nlm.nih.gov/pubmed/35464368
http://dx.doi.org/10.3389/fvets.2022.884357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024361/
https://www.ncbi.nlm.nih.gov/pubmed/35464368
http://dx.doi.org/10.3389/fvets.2022.884357

Ejemplares similares