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Pharmacokinetics, Tissue Distribution, Metabolism and Excretion of a Novel COX-2 Inhibitor, Vitacoxib, in Rats

The objectives of this study were to elucidate absorption, tissue distribution, excretion, and metabolism of vitacoxib, a novel selective cyclooxygenase-2 inhibitor, in Wistar rats. Vitacoxib was detected in most tissues within 15 min, suggesting that it was well distributed. Moreover, it could cros...

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Detalles Bibliográficos
Autores principales:	Wang, Jianzhong, Kong, Jingyuan, Yang, Yuxin, Liu, Yu, Qiu, Jicheng, Gong, Xiaohui, Zhang, Lu, Li, Jing, Sun, Feifei, Cao, Xingyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024361/ https://www.ncbi.nlm.nih.gov/pubmed/35464368 http://dx.doi.org/10.3389/fvets.2022.884357

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