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Papulonodular Mucinosis Associated With Subacute Lupus
Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024385/ https://www.ncbi.nlm.nih.gov/pubmed/35475094 http://dx.doi.org/10.7759/cureus.23412 |
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author | Rabba, Sabrine Hali, Fouzia Marnissi, Farida Chiheb, Soumiya |
author_facet | Rabba, Sabrine Hali, Fouzia Marnissi, Farida Chiheb, Soumiya |
author_sort | Rabba, Sabrine |
collection | PubMed |
description | Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report a case of papulonodular mucinosis associated with SCLE in a middle-aged woman. On physical examination, she presented with multiple flesh-coloured asymptomatic papules and nodules on the trunk and upper extremities. A biopsy specimen taken from a nodule showed mucin within the dermis with hypodermis and perivascular lymphocytic inflammation. Considering that the proportion of patients with cutaneous lupus mucinosis who progress to systemic lupus is uncertain, we suggest following these patients closely for evidence of multisystem disease. |
format | Online Article Text |
id | pubmed-9024385 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-90243852022-04-25 Papulonodular Mucinosis Associated With Subacute Lupus Rabba, Sabrine Hali, Fouzia Marnissi, Farida Chiheb, Soumiya Cureus Dermatology Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report a case of papulonodular mucinosis associated with SCLE in a middle-aged woman. On physical examination, she presented with multiple flesh-coloured asymptomatic papules and nodules on the trunk and upper extremities. A biopsy specimen taken from a nodule showed mucin within the dermis with hypodermis and perivascular lymphocytic inflammation. Considering that the proportion of patients with cutaneous lupus mucinosis who progress to systemic lupus is uncertain, we suggest following these patients closely for evidence of multisystem disease. Cureus 2022-03-23 /pmc/articles/PMC9024385/ /pubmed/35475094 http://dx.doi.org/10.7759/cureus.23412 Text en Copyright © 2022, Rabba et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Rabba, Sabrine Hali, Fouzia Marnissi, Farida Chiheb, Soumiya Papulonodular Mucinosis Associated With Subacute Lupus |
title | Papulonodular Mucinosis Associated With Subacute Lupus |
title_full | Papulonodular Mucinosis Associated With Subacute Lupus |
title_fullStr | Papulonodular Mucinosis Associated With Subacute Lupus |
title_full_unstemmed | Papulonodular Mucinosis Associated With Subacute Lupus |
title_short | Papulonodular Mucinosis Associated With Subacute Lupus |
title_sort | papulonodular mucinosis associated with subacute lupus |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024385/ https://www.ncbi.nlm.nih.gov/pubmed/35475094 http://dx.doi.org/10.7759/cureus.23412 |
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