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Papulonodular Mucinosis Associated With Subacute Lupus

Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report...

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Autores principales: Rabba, Sabrine, Hali, Fouzia, Marnissi, Farida, Chiheb, Soumiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024385/
https://www.ncbi.nlm.nih.gov/pubmed/35475094
http://dx.doi.org/10.7759/cureus.23412
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author Rabba, Sabrine
Hali, Fouzia
Marnissi, Farida
Chiheb, Soumiya
author_facet Rabba, Sabrine
Hali, Fouzia
Marnissi, Farida
Chiheb, Soumiya
author_sort Rabba, Sabrine
collection PubMed
description Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report a case of papulonodular mucinosis associated with SCLE in a middle-aged woman. On physical examination, she presented with multiple flesh-coloured asymptomatic papules and nodules on the trunk and upper extremities. A biopsy specimen taken from a nodule showed mucin within the dermis with hypodermis and perivascular lymphocytic inflammation. Considering that the proportion of patients with cutaneous lupus mucinosis who progress to systemic lupus is uncertain, we suggest following these patients closely for evidence of multisystem disease.
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spelling pubmed-90243852022-04-25 Papulonodular Mucinosis Associated With Subacute Lupus Rabba, Sabrine Hali, Fouzia Marnissi, Farida Chiheb, Soumiya Cureus Dermatology Papulonodular mucinosis is a rare but well-documented finding associated with systemic and cutaneous forms of lupus erythematosus (LE). It occurs exceptionally in association with subacute cutaneous lupus erythematosus (SCLE). Its etiology and pathogenesis remain to be elucidated. Herein, we report a case of papulonodular mucinosis associated with SCLE in a middle-aged woman. On physical examination, she presented with multiple flesh-coloured asymptomatic papules and nodules on the trunk and upper extremities. A biopsy specimen taken from a nodule showed mucin within the dermis with hypodermis and perivascular lymphocytic inflammation. Considering that the proportion of patients with cutaneous lupus mucinosis who progress to systemic lupus is uncertain, we suggest following these patients closely for evidence of multisystem disease. Cureus 2022-03-23 /pmc/articles/PMC9024385/ /pubmed/35475094 http://dx.doi.org/10.7759/cureus.23412 Text en Copyright © 2022, Rabba et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Rabba, Sabrine
Hali, Fouzia
Marnissi, Farida
Chiheb, Soumiya
Papulonodular Mucinosis Associated With Subacute Lupus
title Papulonodular Mucinosis Associated With Subacute Lupus
title_full Papulonodular Mucinosis Associated With Subacute Lupus
title_fullStr Papulonodular Mucinosis Associated With Subacute Lupus
title_full_unstemmed Papulonodular Mucinosis Associated With Subacute Lupus
title_short Papulonodular Mucinosis Associated With Subacute Lupus
title_sort papulonodular mucinosis associated with subacute lupus
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024385/
https://www.ncbi.nlm.nih.gov/pubmed/35475094
http://dx.doi.org/10.7759/cureus.23412
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