Pan-Phosphodiesterase Inhibitors Attenuate TGF-β-Induced Pro-Fibrotic Phenotype in Alveolar Epithelial Type II Cells by Downregulating Smad-2 Phosphorylation

Airway remodeling is a pathological process that accompanies many chronic lung diseases. One of the important players in this process are epithelial cells, which under the influence of pro-inflammatory and pro-fibrotic factors present in the airway niche, actively participate in the remodeling proce...

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Detalles Bibliográficos
Autores principales: Wójcik-Pszczoła, Katarzyna, Chłoń-Rzepa, Grażyna, Jankowska, Agnieszka, Ferreira, Bruno, Koczurkiewicz-Adamczyk, Paulina, Pękala, Elżbieta, Wyska, Elżbieta, Pociecha, Krzysztof, Gosens, Reinoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024446/
https://www.ncbi.nlm.nih.gov/pubmed/35455420
http://dx.doi.org/10.3390/ph15040423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024446/
https://www.ncbi.nlm.nih.gov/pubmed/35455420
http://dx.doi.org/10.3390/ph15040423

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