Restricted Activation of the NF-κB Pathway in Individuals with Latent Tuberculosis Infection after HIF-1α Blockade

Tuberculous granuloma formation is mediated by hypoxia-inducible factor 1 alpha (HIF-1α), and is essential for establishing latent tuberculosis infection (LTBI) and its progression to active tuberculosis (TB). Here, we investigated whether HIF-1α expression and adjacent mechanisms were associated wi...

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Detalles Bibliográficos
Autores principales: de Oliveira Rezende, Aline, Sabóia, Rafaella Santos, da Costa, Adeliane Castro, da Silva Monteiro, Diana Messala Pinheiro, Zagmignan, Adrielle, Santiago, Luis Ângelo Macedo, Carvalho, Rafael Cardoso, Pereira, Paulo Vitor Soeiro, Junqueira-Kipnis, Ana Paula, de Sousa, Eduardo Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024452/
https://www.ncbi.nlm.nih.gov/pubmed/35453567
http://dx.doi.org/10.3390/biomedicines10040817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024452/
https://www.ncbi.nlm.nih.gov/pubmed/35453567
http://dx.doi.org/10.3390/biomedicines10040817

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