Lethal Mutagenesis of RNA Viruses and Approved Drugs with Antiviral Mutagenic Activity

In RNA viruses, a small increase in their mutation rates can be sufficient to exceed their threshold of viability. Lethal mutagenesis is a therapeutic strategy based on the use of mutagens, driving viral populations to extinction. Extinction catastrophe can be experimentally induced by promutagenic...

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Detalles Bibliográficos
Autores principales: Hadj Hassine, Ikbel, Ben M’hadheb, Manel, Menéndez-Arias, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024455/
https://www.ncbi.nlm.nih.gov/pubmed/35458571
http://dx.doi.org/10.3390/v14040841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024455/
https://www.ncbi.nlm.nih.gov/pubmed/35458571
http://dx.doi.org/10.3390/v14040841

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