P144 a Transforming Growth Factor Beta Inhibitor Peptide, Generates Antifibrogenic Effects in a Radiotherapy Induced Fibrosis Model

Radiation-induced fibrosis (RIF) is a severe side effect related with soft tissues sarcomas (STS) radiotherapy. RIF is a multicellular process initiated primarily by TGF-β1 that is increased in irradiated tissue, whose signaling leads to intracellular Smad2/3 phosphorylation and further induction of...

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Detalles Bibliográficos
Autores principales: Cruz-Morande, Sebastián, Dotor, Javier, San-Julian, Mikel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024500/
https://www.ncbi.nlm.nih.gov/pubmed/35448191
http://dx.doi.org/10.3390/curroncol29040217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024500/
https://www.ncbi.nlm.nih.gov/pubmed/35448191
http://dx.doi.org/10.3390/curroncol29040217

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