Stereoselective Synthesis of β-Glycinamide Ribonucleotide

A diastereoselective synthesis of the β-anomer of glycinamide ribonucleotide (β-GAR) has been developed. The synthesis was accomplished in nine steps from D-ribose and occurred in 5% overall yield. The route provided material on the multi-milligram scale. The synthetic β-GAR formed was remarkably re...

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Detalles Bibliográficos
Autores principales: Ngu, Lisa, Ray, Debarpita, Watson, Samantha S., Beuning, Penny J., Ondrechen, Mary Jo, O’Doherty, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024515/
https://www.ncbi.nlm.nih.gov/pubmed/35458726
http://dx.doi.org/10.3390/molecules27082528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024515/
https://www.ncbi.nlm.nih.gov/pubmed/35458726
http://dx.doi.org/10.3390/molecules27082528

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