4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives

A new set of amino-3,5-dicyanopyridines was synthesized and biologically evaluated at the adenosine receptors (ARs). This chemical class is particularly versatile, as small structural modifications can influence not only affinity and selectivity, but also the pharmacological profile. Thus, in order...

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Detalles Bibliográficos
Autores principales: Catarzi, Daniela, Varano, Flavia, Vigiani, Erica, Calenda, Sara, Melani, Fabrizio, Varani, Katia, Vincenzi, Fabrizio, Pasquini, Silvia, Mennini, Natascia, Nerli, Giulia, Dal Ben, Diego, Volpini, Rosaria, Colotta, Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024521/
https://www.ncbi.nlm.nih.gov/pubmed/35455475
http://dx.doi.org/10.3390/ph15040478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024521/
https://www.ncbi.nlm.nih.gov/pubmed/35455475
http://dx.doi.org/10.3390/ph15040478

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