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Self-Assembled Nanomicellar Formulation of Docetaxel as a Potential Breast Cancer Chemotherapeutic System

Docetaxel (DTX) is classified as a class IV drug that exhibits poor aqueous solubility (6–7 µg/mL in water) and permeability (P-glycoprotein substrate). The main objective of this study was to construct, characterize, and evaluate docetaxel loaded nanomicellar formulation in vitro for oral delivery...

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Detalles Bibliográficos
Autores principales: Alshamrani, Meshal, Ayon, Navid J., Alsalhi, Abdullah, Akinjole, Omowumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024535/
https://www.ncbi.nlm.nih.gov/pubmed/35454976
http://dx.doi.org/10.3390/life12040485