Novel Compound Inhibitors of HIV-1(NL4-3) Vpu

HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate the contribution of Vpu to pathogenesis and lay th...

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Detalles Bibliográficos
Autores principales: Robinson, Carolyn A., Lyddon, Terri D., Gil, Hwi Min, Evans, David T., Kuzmichev, Yury V., Richard, Jonathan, Finzi, Andrés, Welbourn, Sarah, Rasmussen, Lynn, Nebane, N. Miranda, Gupta, Vandana V., Ananthan, Sam, Cai, Zhaohui, Wonderlich, Elizabeth R., Augelli-Szafran, Corinne E., Bostwick, Robert, Ptak, Roger G., Schader, Susan M., Johnson, Marc C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024541/
https://www.ncbi.nlm.nih.gov/pubmed/35458546
http://dx.doi.org/10.3390/v14040817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024541/
https://www.ncbi.nlm.nih.gov/pubmed/35458546
http://dx.doi.org/10.3390/v14040817

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