Improving Tirapazamine (TPZ) to Target and Eradicate Hypoxia Tumors by Gold Nanoparticle Carriers

Tumor hypoxia is a hallmark of solid tumors and emerged as the therapeutic target for cancer treatments, such as a prodrug Tirapazamine (TPZ) activated in hypoxia. To increase tumor accumulation, gold nanoparticles (GNPs) were selected to conjugate with TPZ. In this study, we successfully formulated...

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Detalles Bibliográficos
Autores principales: Ajnai, Giimel, Cheng, Chun-Chia, Kan, Tzu-Chun, Lu, Jeng-Wei, Rahayu, Sri, Chiu, Amy, Chang, Jungshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024542/
https://www.ncbi.nlm.nih.gov/pubmed/35456681
http://dx.doi.org/10.3390/pharmaceutics14040847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024542/
https://www.ncbi.nlm.nih.gov/pubmed/35456681
http://dx.doi.org/10.3390/pharmaceutics14040847

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