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Improving Tirapazamine (TPZ) to Target and Eradicate Hypoxia Tumors by Gold Nanoparticle Carriers

Tumor hypoxia is a hallmark of solid tumors and emerged as the therapeutic target for cancer treatments, such as a prodrug Tirapazamine (TPZ) activated in hypoxia. To increase tumor accumulation, gold nanoparticles (GNPs) were selected to conjugate with TPZ. In this study, we successfully formulated...

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Detalles Bibliográficos
Autores principales:	Ajnai, Giimel, Cheng, Chun-Chia, Kan, Tzu-Chun, Lu, Jeng-Wei, Rahayu, Sri, Chiu, Amy, Chang, Jungshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024542/ https://www.ncbi.nlm.nih.gov/pubmed/35456681 http://dx.doi.org/10.3390/pharmaceutics14040847

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