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A Boolean Model of the Proliferative Role of the lncRNA XIST in Non-Small Cell Lung Cancer Cells

SIMPLE SUMMARY: The lncRNA XIST has been verified as an oncogenic gene in non-small cell lung cancer (NSCLC), whereas the tumor suppressors miR-34a, miR-449a, and miR-16 were downregulated in NSCLC. The lncRNA XIST is known to bind to the miR-449a and miR-34a sponges, however, the biological functio...

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Detalles Bibliográficos
Autores principales: Gupta, Shantanu, Silveira, Daner A., Hashimoto, Ronaldo F., Mombach, Jose Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024590/
https://www.ncbi.nlm.nih.gov/pubmed/35453680
http://dx.doi.org/10.3390/biology11040480