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Role of Bevacizumab on Vascular Endothelial Growth Factor in Apolipoprotein E Deficient Mice after Traumatic Brain Injury

Traumatic brain injury (TBI) disrupts the blood–brain barrier (BBB). Vascular endothelial growth factor (VEGF) is believed to play a key role in TBI and to be overexpressed in the absence of apolipoprotein E (ApoE). Bevacizumab, a VEGF inhibitor, demonstrated neuroprotective activity in several mode...

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Detalles Bibliográficos
Autores principales: Genovese, Tiziana, Impellizzeri, Daniela, D’Amico, Ramona, Fusco, Roberta, Peritore, Alessio Filippo, Di Paola, Davide, Interdonato, Livia, Gugliandolo, Enrico, Crupi, Rosalia, Di Paola, Rosanna, Cuzzocrea, Salvatore, Cordaro, Marika, Siracusa, Rosalba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024601/
https://www.ncbi.nlm.nih.gov/pubmed/35456980
http://dx.doi.org/10.3390/ijms23084162