Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen

Bitiscetin-1 (aka bitiscetin) and bitiscetin-2 are C-type lectin-like proteins purified from the venom of Bitis arietans (puff adder). They bind to von Willebrand factor (VWF) and—at least bitiscetin-1—induce platelet agglutination via enhancement of VWF binding to platelet glycoprotein Ib (GPIb). B...

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Detalles Bibliográficos
Autores principales: Nashimoto, Youhei, Matsushita, Fumio, Dijkstra, Johannes M., Nakamura, Yuta, Akiyama, Hidehiko, Hamako, Jiharu, Morita, Takashi, Araki, Satohiko, Matsui, Taei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024624/
https://www.ncbi.nlm.nih.gov/pubmed/35448845
http://dx.doi.org/10.3390/toxins14040236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024624/
https://www.ncbi.nlm.nih.gov/pubmed/35448845
http://dx.doi.org/10.3390/toxins14040236

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