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Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease

Renal cyst expansion in polycystic kidney disease (PKD) involves abnormalities in both cyst-lining-cell proliferation and fluid accumulation. Suppression of these processes may retard the progression of PKD. Evidence suggests that the activation of 5′ AMP-activated protein kinase (AMPK) inhibits cys...

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Detalles Bibliográficos
Autores principales: Tonum, Kanlayanee, Srimai, Nipitpon, Chabang, Napason, Fongsupa, Somsak, Tuchinda, Patoomratana, Torres, Jacob A., Weimbs, Thomas, Soodvilai, Sunhapas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024631/
https://www.ncbi.nlm.nih.gov/pubmed/35457146
http://dx.doi.org/10.3390/ijms23084328