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Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease
Renal cyst expansion in polycystic kidney disease (PKD) involves abnormalities in both cyst-lining-cell proliferation and fluid accumulation. Suppression of these processes may retard the progression of PKD. Evidence suggests that the activation of 5′ AMP-activated protein kinase (AMPK) inhibits cys...
Autores principales: | Tonum, Kanlayanee, Srimai, Nipitpon, Chabang, Napason, Fongsupa, Somsak, Tuchinda, Patoomratana, Torres, Jacob A., Weimbs, Thomas, Soodvilai, Sunhapas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024631/ https://www.ncbi.nlm.nih.gov/pubmed/35457146 http://dx.doi.org/10.3390/ijms23084328 |
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