Formulation and Evaluation of Transdermal Gel Containing Tacrolimus-Loaded Spanlastics: In Vitro, Ex Vivo and In Vivo Studies

Our goal was to prepare Span 60-based elastic nanovesicles (spanlastics (SPLs)) of tacrolimus (TCR) using the adapted ethanol injection method, characterize them, and evaluate their ability to improve the transdermal permeation of the active substance. The impact of two different concentrations of p...

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Detalles Bibliográficos
Autores principales: Zaki, Randa Mohammed, Ibrahim, Mohamed A., Alshora, Doaa H., El Ela, Amal El Sayeh Abou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024636/
https://www.ncbi.nlm.nih.gov/pubmed/35458277
http://dx.doi.org/10.3390/polym14081528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024636/
https://www.ncbi.nlm.nih.gov/pubmed/35458277
http://dx.doi.org/10.3390/polym14081528

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