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Formulation and Evaluation of Transdermal Gel Containing Tacrolimus-Loaded Spanlastics: In Vitro, Ex Vivo and In Vivo Studies
Our goal was to prepare Span 60-based elastic nanovesicles (spanlastics (SPLs)) of tacrolimus (TCR) using the adapted ethanol injection method, characterize them, and evaluate their ability to improve the transdermal permeation of the active substance. The impact of two different concentrations of p...
Autores principales: | Zaki, Randa Mohammed, Ibrahim, Mohamed A., Alshora, Doaa H., El Ela, Amal El Sayeh Abou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024636/ https://www.ncbi.nlm.nih.gov/pubmed/35458277 http://dx.doi.org/10.3390/polym14081528 |
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