In Search of Differential Inhibitors of Aldose Reductase

Aldose reductase, classified within the aldo-keto reductase family as AKR1B1, is an NADPH dependent enzyme that catalyzes the reduction of hydrophilic as well as hydrophobic aldehydes. AKR1B1 is the first enzyme of the so-called polyol pathway that allows the conversion of glucose into sorbitol, whi...

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Detalles Bibliográficos
Autores principales: Balestri, Francesco, Moschini, Roberta, Mura, Umberto, Cappiello, Mario, Del Corso, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024650/
https://www.ncbi.nlm.nih.gov/pubmed/35454074
http://dx.doi.org/10.3390/biom12040485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024650/
https://www.ncbi.nlm.nih.gov/pubmed/35454074
http://dx.doi.org/10.3390/biom12040485

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