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A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers

An emerging target to overcome cancer resistance to treatments is copper, which is upregulated in a wide variety of tumors and may be associated with cancer progression and metastases. The aim of this study was to develop a multimodal ultrasmall nanoparticle, CuPRiX, based on the clinical AGuIX nano...

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Detalles Bibliográficos
Autores principales: Rocchi, Paul, Brichart-Vernos, Delphine, Lux, François, Morfin, Isabelle, David, Laurent, Rodriguez-Lafrasse, Claire, Tillement, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024746/
https://www.ncbi.nlm.nih.gov/pubmed/35456648
http://dx.doi.org/10.3390/pharmaceutics14040814