Cargando…
A New Generation of Ultrasmall Nanoparticles Inducing Sensitization to Irradiation and Copper Depletion to Overcome Radioresistant and Invasive Cancers
An emerging target to overcome cancer resistance to treatments is copper, which is upregulated in a wide variety of tumors and may be associated with cancer progression and metastases. The aim of this study was to develop a multimodal ultrasmall nanoparticle, CuPRiX, based on the clinical AGuIX nano...
Autores principales: | Rocchi, Paul, Brichart-Vernos, Delphine, Lux, François, Morfin, Isabelle, David, Laurent, Rodriguez-Lafrasse, Claire, Tillement, Olivier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024746/ https://www.ncbi.nlm.nih.gov/pubmed/35456648 http://dx.doi.org/10.3390/pharmaceutics14040814 |
Ejemplares similares
-
Proof of Concept of the Radiosensitizing Effect of Gadolinium Oxide Nanoparticles in Cell Spheroids and a Tumor-Implanted Murine Model of Chondrosarcoma
por: Aloy, Marie-Thérèse, et al.
Publicado: (2022) -
Identification of Molecular Fragments in Equilibrium with Polysiloxane Ultrasmall Nanoparticles
por: Rocchi, Paul, et al.
Publicado: (2022) -
Involvement of HIF-1α in the Detection, Signaling, and Repair of DNA Double-Strand Breaks after Photon and Carbon-Ion Irradiation
por: Wozny, Anne-Sophie, et al.
Publicado: (2021) -
EPR-mediated tumor targeting using ultrasmall-hybrid nanoparticles: From animal to human with theranostic AGuIX nanoparticles
por: Bort, Guillaume, et al.
Publicado: (2020) -
Iron as an emerging therapeutic target in critically ill patients
por: Grange, Coralie, et al.
Publicado: (2023)