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Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment

The human telomere region is known to contain guanine-rich repeats and form a guanine-quadruplex (G4) structure. As telomeres play a role in the regulation of cancer progression, ligands that specifically bind and stabilize G4 have potential therapeutic applications. However, as the human telomere s...

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Detalles Bibliográficos
Autores principales: Takahashi, Shuntaro, Bhowmik, Sudipta, Sato, Shinobu, Takenaka, Shigeori, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024748/
https://www.ncbi.nlm.nih.gov/pubmed/35455044
http://dx.doi.org/10.3390/life12040553