Cargando…

Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment

The human telomere region is known to contain guanine-rich repeats and form a guanine-quadruplex (G4) structure. As telomeres play a role in the regulation of cancer progression, ligands that specifically bind and stabilize G4 have potential therapeutic applications. However, as the human telomere s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takahashi, Shuntaro, Bhowmik, Sudipta, Sato, Shinobu, Takenaka, Shigeori, Sugimoto, Naoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024748/ https://www.ncbi.nlm.nih.gov/pubmed/35455044 http://dx.doi.org/10.3390/life12040553

Ejemplares similares

A Selective G-Quadruplex DNA-Stabilizing Ligand Based on a Cyclic Naphthalene Diimide Derivative
por: Islam, Md. Monirul, et al.
Publicado: (2015)

Naphthalene Diimides Carrying Two β-Cyclodextrins Prefer Telomere RNA G-Quadruplex Recognition
por: Zou, Tingting, et al.
Publicado: (2022)

The Interaction of Cyclic Naphthalene Diimide with G-Quadruplex under Molecular Crowding Condition
por: Zou, Tingting, et al.
Publicado: (2020)

Design and Properties of Ligand-Conjugated Guanine Oligonucleotides for Recovery of Mutated G-Quadruplexes
por: Takahashi, Shuntaro, et al.
Publicado: (2018)

Stability of telomeric G-quadruplexes
por: Tran, Phong Lan Thao, et al.
Publicado: (2011)

G-Quadruplexes and Their Ligands: Biophysical Methods to Unravel G-Quadruplex/Ligand Interactions
por: Santos, Tiago, et al.
Publicado: (2021)

Effect of Pressure on Thermal Stability of G-Quadruplex DNA and Double-Stranded DNA Structures
por: Takahashi, Shuntaro, et al.
Publicado: (2013)

Human replication protein A unfolds telomeric G-quadruplexes
por: Salas, Tonatiuh Romero, et al.
Publicado: (2006)

Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes
por: Bončina, Matjaž, et al.
Publicado: (2015)

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
por: Ruggiero, Emanuela, et al.
Publicado: (2018)

G-Quadruplexes at Telomeres: Friend or Foe?
por: Bryan, Tracy M.
Publicado: (2020)

Replication of G Quadruplex DNA
por: Lerner, Leticia Koch, et al.
Publicado: (2019)

Thrombin binding aptamer G-quadruplex stabilized by pyrene-modified nucleotides
por: Kovačič, Matic, et al.
Publicado: (2020)

Role of ATM in the telomere response to the G-quadruplex ligand 360A
por: Pennarun, Gaëlle, et al.
Publicado: (2008)

Dynamic interaction of BRCA2 with telomeric G-quadruplexes underlies telomere replication homeostasis
por: Lee, Junyeop, et al.
Publicado: (2022)

Detection of CpG Methylation in G-Quadruplex Forming Sequences Using G-Quadruplex Ligands
por: Hasegawa, Hijiri, et al.
Publicado: (2021)

The G-Quadruplex Ligand Telomestatin Impairs Binding of Topoisomerase IIIα to G-Quadruplex-Forming Oligonucleotides and Uncaps Telomeres in ALT Cells
por: Temime-Smaali, Nassima, et al.
Publicado: (2009)

Inhibition of Zika virus replication by G-quadruplex-binding ligands
por: Majee, Prativa, et al.
Publicado: (2021)

The solution structures of higher-order human telomere G-quadruplex multimers
por: Monsen, Robert C, et al.
Publicado: (2021)

Characterization of G-Quadruplexes in Enterovirus A71 Genome and Their Interaction with G-Quadruplex Ligands
por: Lv, Lu, et al.
Publicado: (2022)

Ion-Dependent Conformational Plasticity of Telomeric G-Hairpins and G-Quadruplexes
por: Salsbury, Alexa M., et al.
Publicado: (2022)

G-quadruplexes mark alternative lengthening of telomeres
por: Yang, Sunny Y, et al.
Publicado: (2021)

Stability of the Na(+) Form of the Human Telomeric G-Quadruplex: Role of Adenines in Stabilizing G-Quadruplex Structure
por: Tucker, Brenna A., et al.
Publicado: (2018)

Cationic Porphyrin Induced a Telomeric DNA to G-Quadruplex Form in Water
por: Murashima, Takashi, et al.
Publicado: (2008)

Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
por: Moraca, Federica, et al.
Publicado: (2017)

Polymorphism and Ligand Binding Modulate Fast Dynamics of Human Telomeric G-Quadruplexes
por: Bertini, Luca, et al.
Publicado: (2023)

G-Quadruplex Aptamer-Ligand Characterization
por: Moreira, David, et al.
Publicado: (2022)

Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K(+) solution: insights into the interconversion of human telomeric G-quadruplex structures
por: Zhang, Zhenjiang, et al.
Publicado: (2010)

Evaluation of Human Telomeric G-Quadruplexes: The Influence of Overhanging Sequences on Quadruplex Stability and Folding
por: Viglasky, Viktor, et al.
Publicado: (2010)

Telomeric G-Quadruplexes: From Human to Tetrahymena Repeats
por: Demkovičová, Erika, et al.
Publicado: (2017)

Impact of Oxidative Lesions on the Human Telomeric G-Quadruplex
por: Bielskutė, Stasė, et al.
Publicado: (2019)

Investigating the role of G-quadruplexes at Saccharomyces cerevisiae telomeres
por: Stinus, Sonia, et al.
Publicado: (2022)

Molecular mechanism of anionic stabilizer for telomere G-quadruplex
por: Wang, Zhiguo, et al.
Publicado: (2022)

Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance
por: Wang, Shi-Ke, et al.
Publicado: (2015)

Using Macrocyclic G‐Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G‐Quadruplex DNA
por: Andréasson, Måns, et al.
Publicado: (2022)

Stability of Human Telomeric G-Quadruplexes Complexed with Photosensitive Ligands and Irradiated with Visible Light
por: Libera, Valeria, et al.
Publicado: (2023)

Ruthenium Polypyridyl Complex Bound to a Unimolecular Chair-Form G-Quadruplex
por: McQuaid, Kane T., et al.
Publicado: (2022)

Cyclic anthraquinone derivatives, unique G-quadruplex binders, selectively induce cancer cell apoptosis and inhibit tumor growth
por: Fukuda, Hikaru, et al.
Publicado: (2023)

Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions
por: Dhakal, Soma, et al.
Publicado: (2013)

Multistep mechanism of G-quadruplex resolution during DNA replication
por: Sato, Koichi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4hqcs05svv76r2ft9v3jp4ggkj