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Engineered Neutral Phosphorous Dendrimers Protect Mouse Cortical Neurons and Brain Organoids from Excitotoxic Death

Nanoparticles are playing an increasing role in biomedical applications. Excitotoxicity plays a significant role in the pathophysiology of neurodegenerative diseases, such as Alzheimer’s or Parkinson’s disease. Glutamate ionotropic receptors, mainly those activated by N-methyl-D-aspartate (NMDA), pl...

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Detalles Bibliográficos
Autores principales: Posadas, Inmaculada, Romero-Castillo, Laura, Ronca, Rosa-Anna, Karpus, Andrii, Mignani, Serge, Majoral, Jean-Pierre, Muñoz-Fernández, Mariángeles, Ceña, Valentín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024777/
https://www.ncbi.nlm.nih.gov/pubmed/35457211
http://dx.doi.org/10.3390/ijms23084391