Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

We evaluated the in vitro permeability of nanoparticle formulations of high and low lipophilic compounds under non-sink conditions, wherein compounds are not completely dissolved. The permeability of the highly lipophilic compound, griseofulvin, was improved by about 30% due to nanonization under no...

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Detalles Bibliográficos
Autores principales: Sugita, Kazuya, Takata, Noriyuki, Yonemochi, Etsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024805/
https://www.ncbi.nlm.nih.gov/pubmed/35456650
http://dx.doi.org/10.3390/pharmaceutics14040816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024805/
https://www.ncbi.nlm.nih.gov/pubmed/35456650
http://dx.doi.org/10.3390/pharmaceutics14040816

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