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Self or Non-Self? It Is also a Matter of RNA Recognition and Editing by ADAR1

SIMPLE SUMMARY: A fundamental feature of innate immune cells is to detect the presence of non-self, such as potentially harmful nucleic acids, by germline-encoded specialized receptors called pattern recognition receptors (PRRs). ADAR1 is one key enzyme avoiding aberrant type I interferon (IFN-I) pr...

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Detalles Bibliográficos
Autores principales: Tassinari, Valentina, Cerboni, Cristina, Soriani, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024829/
https://www.ncbi.nlm.nih.gov/pubmed/35453767
http://dx.doi.org/10.3390/biology11040568