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Pharmacokinetics of DA-6886, A New 5-HT(4) Receptor Agonist, in Rats

DA-6886 is a novel serotonin (5-hydroxytrypamine [5-HT]) receptor 4 agonist for the potential treatment of constipation-predominant irritable bowel syndrome. The purpose of this study was to validate the quantitative assay of DA-6886 in rat plasma and to evaluate the pharmacokinetics and tissue dist...

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Detalles Bibliográficos
Autores principales: Lee, Dae Young, Kang, Hee Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024849/
https://www.ncbi.nlm.nih.gov/pubmed/35456538
http://dx.doi.org/10.3390/pharmaceutics14040702