1,2,4-Trioxolane and 1,2,4,5-Tetraoxane Endoperoxides against Old-World Leishmania Parasites: In Vitro Activity and Mode of Action

Leishmaniasis remains one of the ten Neglected Tropical Diseases with significant morbidity and mortality in humans. Current treatment of visceral leishmaniasis is difficult due to a lack of effective, non-toxic, and non-extensive medications. This study aimed to evaluate the selectivity of 12 synth...

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Detalles Bibliográficos
Autores principales: Mendes, Andreia, Armada, Ana, Cabral, Lília I. L., Amado, Patrícia S. M., Campino, Lenea, Cristiano, Maria L. S., Cortes, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024893/
https://www.ncbi.nlm.nih.gov/pubmed/35455443
http://dx.doi.org/10.3390/ph15040446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024893/
https://www.ncbi.nlm.nih.gov/pubmed/35455443
http://dx.doi.org/10.3390/ph15040446

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