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1,2,4-Trioxolane and 1,2,4,5-Tetraoxane Endoperoxides against Old-World Leishmania Parasites: In Vitro Activity and Mode of Action
Leishmaniasis remains one of the ten Neglected Tropical Diseases with significant morbidity and mortality in humans. Current treatment of visceral leishmaniasis is difficult due to a lack of effective, non-toxic, and non-extensive medications. This study aimed to evaluate the selectivity of 12 synth...
Autores principales: | Mendes, Andreia, Armada, Ana, Cabral, Lília I. L., Amado, Patrícia S. M., Campino, Lenea, Cristiano, Maria L. S., Cortes, Sofia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024893/ https://www.ncbi.nlm.nih.gov/pubmed/35455443 http://dx.doi.org/10.3390/ph15040446 |
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