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N-VEGF, the Autoregulatory Arm of VEGF-A

Vascular endothelial growth factor A (VEGF-A) is a secreted protein that stimulates angiogenesis in response to hypoxia. Under hypoxic conditions, a non-canonical long isoform called L-VEGF is concomitantly expressed with VEGF-A. Once translated, L-VEGF is proteolytically cleaved to generate N-VEGF...

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Detalles Bibliográficos
Autores principales: Katsman, Marina, Azriel, Aviva, Horev, Guy, Reizel, Yitzhak, Levi, Ben-Zion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024919/
https://www.ncbi.nlm.nih.gov/pubmed/35455969
http://dx.doi.org/10.3390/cells11081289