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N-VEGF, the Autoregulatory Arm of VEGF-A
Vascular endothelial growth factor A (VEGF-A) is a secreted protein that stimulates angiogenesis in response to hypoxia. Under hypoxic conditions, a non-canonical long isoform called L-VEGF is concomitantly expressed with VEGF-A. Once translated, L-VEGF is proteolytically cleaved to generate N-VEGF...
Autores principales: | Katsman, Marina, Azriel, Aviva, Horev, Guy, Reizel, Yitzhak, Levi, Ben-Zion |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024919/ https://www.ncbi.nlm.nih.gov/pubmed/35455969 http://dx.doi.org/10.3390/cells11081289 |
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