Design and Synthesis of Some New Furan-Based Derivatives and Evaluation of In Vitro Cytotoxic Activity

New furan-based derivatives have been, designed, synthesized, and evaluated for their cytotoxic and tubulin polymerization inhibitory activities. DNA flow cytometric study of pyridine carbohydrazide 4 and N-phenyl triazinone 7 demonstrated G(2)/M phase cell cycle disruptions. Accumulation of cells i...

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Detalles Bibliográficos
Autores principales: Bukhari, Syed Nasir Abbas, Ejaz, Hasan, Elsherif, Mervat A., Junaid, Kashaf, Zaki, Islam, Masoud, Reham E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024937/
https://www.ncbi.nlm.nih.gov/pubmed/35458804
http://dx.doi.org/10.3390/molecules27082606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024937/
https://www.ncbi.nlm.nih.gov/pubmed/35458804
http://dx.doi.org/10.3390/molecules27082606

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