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Design and Synthesis of Some New Furan-Based Derivatives and Evaluation of In Vitro Cytotoxic Activity
New furan-based derivatives have been, designed, synthesized, and evaluated for their cytotoxic and tubulin polymerization inhibitory activities. DNA flow cytometric study of pyridine carbohydrazide 4 and N-phenyl triazinone 7 demonstrated G(2)/M phase cell cycle disruptions. Accumulation of cells i...
Autores principales: | Bukhari, Syed Nasir Abbas, Ejaz, Hasan, Elsherif, Mervat A., Junaid, Kashaf, Zaki, Islam, Masoud, Reham E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024937/ https://www.ncbi.nlm.nih.gov/pubmed/35458804 http://dx.doi.org/10.3390/molecules27082606 |
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