Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation

As a widely distributed parasitic nematode of ruminants, Haemonchus contortus has become resistant to most anthelmintic classes, there has been a major demand for new compounds against H. contortus and related nematodes. Recent phenotypic screening has revealed two compounds, designated as BLK127 an...

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Detalles Bibliográficos
Autores principales: Zajíčková, Markéta, Prchal, Lukáš, Vokřál, Ivan, Nguyen, Linh Thuy, Kurz, Thomas, Gasser, Robin, Bednářová, Klára, Mičundová, Magdalena, Lungerich, Beate, Michel, Oliver, Skálová, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024958/
https://www.ncbi.nlm.nih.gov/pubmed/35456588
http://dx.doi.org/10.3390/pharmaceutics14040754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9024958/
https://www.ncbi.nlm.nih.gov/pubmed/35456588
http://dx.doi.org/10.3390/pharmaceutics14040754

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