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Development of Solvent-Free Co-Ground Method to Produce Terbinafine Hydrochloride Cyclodextrin Binary Systems; Structural and In Vitro Characterizations

Molecular complexation with cyclodextrins (CDs) has long been a known process for modifying the physicochemical properties of problematic active pharmaceutical ingredients with poor water solubility. In current times, the focus has been on the solvent-free co-grinding process, which is an industrial...

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Detalles Bibliográficos
Autores principales: Kondoros, Balázs Attila, Jójárt-Laczkovich, Orsolya, Berkesi, Ottó, Szabó-Révész, Piroska, Csóka, Ildikó, Ambrus, Rita, Aigner, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025016/
https://www.ncbi.nlm.nih.gov/pubmed/35456578
http://dx.doi.org/10.3390/pharmaceutics14040744