Loss and Recovery of Glutaredoxin 5 Is Inducible by Diet in a Murine Model of Diabesity and Mediated by Free Fatty Acids In Vitro

Free fatty acids (FFA), hyperglycemia, and inflammatory cytokines are major mediators of β-cell toxicity in type 2 diabetes mellitus, impairing mitochondrial metabolism. Glutaredoxin 5 (Glrx5) is a mitochondrial protein involved in the assembly of iron–sulfur clusters required for complexes of the r...

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Detalles Bibliográficos
Autores principales: Petry, Sebastian Friedrich, Römer, Axel, Rawat, Divya, Brunner, Lara, Lerch, Nina, Zhou, Mengmeng, Grewal, Rekha, Sharifpanah, Fatemeh, Sauer, Heinrich, Eckert, Gunter Peter, Linn, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025089/
https://www.ncbi.nlm.nih.gov/pubmed/35453472
http://dx.doi.org/10.3390/antiox11040788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025089/
https://www.ncbi.nlm.nih.gov/pubmed/35453472
http://dx.doi.org/10.3390/antiox11040788

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