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Esculetin and Fucoidan Attenuate Autophagy and Apoptosis Induced by Zinc Oxide Nanoparticles through Modulating Reactive Astrocyte and Proinflammatory Cytokines in the Rat Brain

We examined the protective effects of esculetin and fucoidan against the neurotoxicity of ZnO NPs in rats. Ninety rats were divided into nine groups and pre-treated with esculetin or fucoidan 1 h before ZnO NP administration on a daily basis for 2 weeks. Serum and brain homogenates were examined by...

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Detalles Bibliográficos
Autores principales: Song, Woo-Ju, Kim, Jeongtae, Shin, Taekyun, Jeong, Myeong-Seon, Kim, Kil-Nam, Yun, Jang-Hyuk, Wie, Myung-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025201/
https://www.ncbi.nlm.nih.gov/pubmed/35448455
http://dx.doi.org/10.3390/toxics10040194