Designing Stable Bacillus anthracis Antigens with a View to Recombinant Anthrax Vaccine Development

Anthrax is a disease caused by Bacillus anthracis that affects mammals, including humans. Recombinant B. anthracis protective antigen (rPA) is the most common basis for modern anthrax vaccine candidates. However, this protein is characterised by low stability due to proteolysis and deamidation. Here...

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Detalles Bibliográficos
Autores principales: Ryabchevskaya, Ekaterina M., Granovskiy, Dmitriy L., Evtushenko, Ekaterina A., Ivanov, Peter A., Kondakova, Olga A., Nikitin, Nikolai A., Karpova, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025368/
https://www.ncbi.nlm.nih.gov/pubmed/35456639
http://dx.doi.org/10.3390/pharmaceutics14040806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025368/
https://www.ncbi.nlm.nih.gov/pubmed/35456639
http://dx.doi.org/10.3390/pharmaceutics14040806

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