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Dioscin Alleviates Cisplatin-Induced Mucositis in Rats by Modulating Gut Microbiota, Enhancing Intestinal Barrier Function and Attenuating TLR4/NF-κB Signaling Cascade

Cisplatin-based chemotherapy causes intestinal mucositis, which causes patients immense suffering and hinders the process of cancer treatment. Dioscin is a natural steroid saponin that exhibits strong anti-inflammatory and immunomodulatory properties. Herein, we investigate the protective effect of...

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Detalles Bibliográficos
Autores principales: Jin, Shengzi, Guan, Tongxu, Wang, Shuang, Hu, Mengxin, Liu, Xingyao, Huang, Siqi, Liu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025408/
https://www.ncbi.nlm.nih.gov/pubmed/35457248
http://dx.doi.org/10.3390/ijms23084431