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Head and Neck Cancer Susceptibility and Metabolism in Fanconi Anemia
SIMPLE SUMMARY: Germline loss-of-function mutations in any of over 20 known Fanconi anemia (FA) genes cause the disorder FA. The FA pathway plays a key role in the repair of DNA interstrand crosslinks (ICLs) and stabilization of stalled replication fork. Epidemiological studies have shown that perso...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025423/ https://www.ncbi.nlm.nih.gov/pubmed/35454946 http://dx.doi.org/10.3390/cancers14082040 |