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Head and Neck Cancer Susceptibility and Metabolism in Fanconi Anemia

SIMPLE SUMMARY: Germline loss-of-function mutations in any of over 20 known Fanconi anemia (FA) genes cause the disorder FA. The FA pathway plays a key role in the repair of DNA interstrand crosslinks (ICLs) and stabilization of stalled replication fork. Epidemiological studies have shown that perso...

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Detalles Bibliográficos
Autores principales: Chihanga, Tafadzwa, Vicente-Muñoz, Sara, Ruiz-Torres, Sonya, Pal, Bidisha, Sertorio, Mathieu, Andreassen, Paul R., Khoury, Ruby, Mehta, Parinda, Davies, Stella M., Lane, Andrew N., Romick-Rosendale, Lindsey E., Wells, Susanne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025423/
https://www.ncbi.nlm.nih.gov/pubmed/35454946
http://dx.doi.org/10.3390/cancers14082040