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DnaJC7 in Amyotrophic Lateral Sclerosis

Protein misfolding is a common basis of many neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Misfolded proteins, such as TDP-43, FUS, Matrin3, and SOD1, mislocalize and form the hallmark cytoplasmic and nuclear inclusions in neurons of ALS patients. Cellular protein quality...

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Detalles Bibliográficos
Autores principales: Dilliott, Allison A., Andary, Catherine M., Stoltz, Meaghan, Petropavlovskiy, Andrey A., Farhan, Sali M. K., Duennwald, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025444/
https://www.ncbi.nlm.nih.gov/pubmed/35456894
http://dx.doi.org/10.3390/ijms23084076