Metabolic Alteration Analysis of Steroid Hormones in Niemann–Pick Disease Type C Model Cell Using Liquid Chromatography/Tandem Mass Spectrometry

Niemann–Pick disease type C (NPC) is an autosomal recessive disease caused by a functional deficiency of cholesterol-transporting proteins in lysosomes, and exhibits various clinical symptoms. Since mitochondrial dysfunction in NPC has recently been reported, cholesterol catabolism to steroid hormon...

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Detalles Bibliográficos
Autores principales: Abe, Ai, Maekawa, Masamitsu, Sato, Toshihiro, Sato, Yu, Kumondai, Masaki, Takahashi, Hayato, Kikuchi, Masafumi, Higaki, Katsumi, Ogura, Jiro, Mano, Nariyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025463/
https://www.ncbi.nlm.nih.gov/pubmed/35457276
http://dx.doi.org/10.3390/ijms23084459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025463/
https://www.ncbi.nlm.nih.gov/pubmed/35457276
http://dx.doi.org/10.3390/ijms23084459

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