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A Small Molecule Promoting Neural Differentiation Suppresses Cancer Stem Cells in Colorectal Cancer

Cancer stem cells (CSCs) are a tumor cell subpopulation that drives tumor progression and metastasis, leading to a poor overall survival of patients. In colorectal cancer (CRC), the hyper-activation of Wnt/β-catenin signaling by a mutation of both adenomatous polyposis coli (APC) and K-Ras increases...

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Detalles Bibliográficos
Autores principales: Choi, Jung Kyu, Kwak, Ihn-Sil, Yoon, Sae-Bom, Cho, Heeyeong, Moon, Byoung-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025482/
https://www.ncbi.nlm.nih.gov/pubmed/35453609
http://dx.doi.org/10.3390/biomedicines10040859