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A Comparison of Evans Blue and 4-(p-Iodophenyl)butyryl Albumin Binding Moieties on an Integrin α(v)β(6) Binding Peptide

Serum albumin binding moieties (ABMs) such as the Evans blue (EB) dye fragment and the 4-(p-iodophenyl)butyryl (IP) have been used to improve the pharmacokinetic profile of many radiopharmaceuticals. The goal of this work was to directly compare these two ABMs when conjugated to an integrin α(v)β(6)...

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Detalles Bibliográficos
Autores principales: Davis, Ryan A., Hausner, Sven H., Harris, Rebecca, Sutcliffe, Julie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025560/
https://www.ncbi.nlm.nih.gov/pubmed/35456579
http://dx.doi.org/10.3390/pharmaceutics14040745