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A Theranostic Nanocomplex Combining with Magnetic Hyperthermia for Enhanced Accumulation and Efficacy of pH-Triggering Polymeric Cisplatin(IV) Prodrugs

Although polymeric platinum(IV) (Pt(IV)) prodrugs can reduce the side effects of cisplatin, the efficacy of the prodrug is still limited by its non-targeted distribution, poor penetration in deep tumor tissue, and low cytotoxicity in tumor cells. To improve the clinical potential of polymeric prodru...

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Detalles Bibliográficos
Autores principales: Qu, Yang, Wang, Zhiqi, Sun, Miao, Zhao, Tian, Zhu, Xuanlei, Deng, Xiaoli, Zhang, Man, Xu, Ying, Liu, Hongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025582/
https://www.ncbi.nlm.nih.gov/pubmed/35455477
http://dx.doi.org/10.3390/ph15040480