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LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons

Defective mitochondrial dynamics in axons have been linked to both developmental and late-onset neurological disorders. Axonal trafficking is in large part governed by the microtubule motors kinesin-1 and cytoplasmic dynein 1 (dynein). Dynein is the primary retrograde transport motor in axons, and m...

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Detalles Bibliográficos
Autores principales: Pandey, Jai P., Shi, Liang, Brebion, Remi A., Smith, Deanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025594/
https://www.ncbi.nlm.nih.gov/pubmed/35465088
http://dx.doi.org/10.3389/fnmol.2022.841047