Cargando…
LIS1 and NDEL1 Regulate Axonal Trafficking of Mitochondria in Mature Neurons
Defective mitochondrial dynamics in axons have been linked to both developmental and late-onset neurological disorders. Axonal trafficking is in large part governed by the microtubule motors kinesin-1 and cytoplasmic dynein 1 (dynein). Dynein is the primary retrograde transport motor in axons, and m...
Autores principales: | Pandey, Jai P., Shi, Liang, Brebion, Remi A., Smith, Deanna S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025594/ https://www.ncbi.nlm.nih.gov/pubmed/35465088 http://dx.doi.org/10.3389/fnmol.2022.841047 |
Ejemplares similares
-
Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
por: Hebbar, Sachin, et al.
Publicado: (2008) -
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein
por: Żyłkiewicz, Eliza, et al.
Publicado: (2011) -
Axotomy Induces Drp1-Dependent Fragmentation of Axonal Mitochondria
por: Kedra, Joseph, et al.
Publicado: (2021) -
Ndel1 Promotes Axon Regeneration via Intermediate Filaments
por: Toth, Cory, et al.
Publicado: (2008) -
Paclitaxel effects on axonal localization and vesicular trafficking of Na(V)1.8
por: Baker, Christopher A., et al.
Publicado: (2023)